Chapter 23 Human pancreas dataset (Muraro)

23.1 Introduction

This performs an analysis of the Muraro et al. (2016) CEL-seq dataset, consisting of human pancreas cells from various donors.

23.2 Analysis code

23.3 Results

23.3.4 Data integration

##          D28     D29     D30    D31
## [1,] 0.02794 0.02225 0.00000 0.0000
## [2,] 0.00176 0.00271 0.03799 0.0000
## [3,] 0.00203 0.00236 0.00201 0.0496

23.3.5 Clustering

##        Donor
## Cluster D28 D29 D30 D31
##       1 103   6  57 113
##       2  30 155 139 163
##       3  61  20  79  95
##       4  88 265 280 220
##       5  13  74  63  43
##       6   7   6   6   5
##       7  22   7  54  26
##       8  11  69   6  39
##       9   5   2   5   9

23.3.6 Clustering

Bibliography

Muraro, M. J., G. Dharmadhikari, D. Grun, N. Groen, T. Dielen, E. Jansen, L. van Gurp, et al. 2016. “A Single-Cell Transcriptome Atlas of the Human Pancreas.” Cell Syst 3 (4):385–94.