Chapter 18 Human pancreas dataset (Grun)

18.1 Introduction

This performs an analysis of the Grun et al. (2016) CEL-seq2 dataset, consisting of human pancreas cells from various donors.

18.3 Results

18.3.4 Data integration

##          D10     D17      D2     D3     D7
## [1,] 0.05924 0.04442 0.00000 0.0000 0.0000
## [2,] 0.00346 0.00611 0.02055 0.0000 0.0000
## [3,] 0.01184 0.01218 0.00556 0.0582 0.0000
## [4,] 0.00478 0.00774 0.00486 0.0103 0.0598

18.3.5 Clustering

##        Donor
## Cluster D10 D17  D2  D3  D7
##       1  33  73  34 121  28
##       2  17  77   3  13  77
##       3  14 130   0  12  61
##       4  29 101  40  37 120
##       5  22  33   9  22  14
##       6   5  13   0   1  10
##       7   4  14   0   3   1
##       8  32   5   4  13   3
##       9   6  17   0   7  32

Bibliography

Grun, D., M. J. Muraro, J. C. Boisset, K. Wiebrands, A. Lyubimova, G. Dharmadhikari, M. van den Born, et al. 2016. “De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data.” Cell Stem Cell 19 (2):266–77.